Opioid-Related Disorder

Problematic opioid use (e.g., heroin, morphine) causing impairment or distress, with signs of dependence and dysfunction.

Etiology (Biopsychosocial Model)

Biological: High addiction potential via opioid receptors.

Psychological: Pain relief reinforcement, trauma history.

Social: Prescription overuse, stigma, poverty, peer influence.

Symptoms & Diagnosis (Mnemonic: TOXIC NOD):

T - Tolerance

O - Obligations unmet

X - eXcessive time using

I - Increased amounts over time

C - Craving

N - Neglect of activities

O - Ongoing use despite harm

D -Danger (e.g., driving)

Treatment

MAT (Methadone, Buprenorphine, Naltrexone)

CBT, contingency management

Harm reduction and detox support

Info

DSM-5-TR Code

F11.20–F11.29 (based on severity)

Prevalence

~0.6%–0.9% in adults; heroin use disorder ~0.1%–0.3%.